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Table 2 *Expression of chemokines and their receptors in the brain of WNV-infected WT and db / db mice at day 8 after infection

From: Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus

Ligand

WT

db/db

Receptor

WT

db/db

CCL1

-2.1

1.1

CCR1

6.1

10

CCL2

279

320

CCR3

5.0

4.4

CCL3

17

260

CCR5

2.2

5.0

CCL4

20

260

CCR7

3.8

8.1

CCL5

113

279

CXCR2

5.0

4.7

CCL7

86

243

CXCR3

-1.8

2.5

CCL8

21

43

CXCR5

-1.8

1.5

CCL9

6.6

3.5

   

CCL11

-1.7

8.7

   

CCL12

65

279

   

CXCL1

4.0

24

   

CXCL5

1.9

2.5

   

CXCL9

394

3628

   

CXCL10

641

4787

   

CXCL11

7.6

80

   

CXCL13

17

56

   
  1. *Changes in the levels of each gene was first normalized to the housekeeping genes and then the fold-change in WNV-infected brains was calculated in comparison to corresponding mock-infected brains.
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Journal of Neuroinflammation

ISSN: 1742-2094