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Table 3 *Expression of cytokines and their receptors in the brains of WNV-infected WT and db / db mice at day 8 after infection

From: Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus

Ligand

WT

db/db

Receptor

WT

db/db

IFNγ

10

113

IL1R1

1.5

1.5

IL-1α

1.8

8.1

IL1R2

4.4

9.4

IL-1β

3.3

11

TNFRSF1A

1.8

7.1

TNF

6.1

92

TNFRSF1B

2.3

4.1

IL-4

-2.1

-4.2

   
  1. *Changes in the levels of each gene was first normalized to the housekeeping genes, and then the fold-change in WNV-infected brains was calculated in comparison to the corresponding mock-infected brains.