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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Neuroinflammation and related neuropathologies in APPSL mice: further value of this in vivomodel of Alzheimer’s disease

Figure 5

Correlation analyses of neuropathological features of APP SL mice of all age groups. (A) Correlation between neuroinflammation markers GFAP or CD11b and soluble or insoluble Aβ levels, fibrillar Aβ (LOC) or lipid peroxidation in the neocortex or hippocampus of APPSL mice over age. Pearson’s correlation coefficient (r) and P value (*P <0.05; **P <0.01; ***P <0.001) are shown. Representative graphs of correlations between GFAP (B) or CD11b (C) and Aβ40 in the cortex over age are given. Abbreviations: glial fibrillary acidic protein: GFAP, amyloid beta: Aβ, analysis of variance: ANOVA, Amyloid Precursor protein carrying the Swedish London mutation: APPSL, probability: P.

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