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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Synergistic white matter protection with acute-on-chronic endotoxin and subsequent asphyxia in preterm fetal sheep

Figure 2

Changes in numbers of immunohistochemically labeled white matter cells. Bar graphs showing numbers of CNPase positive cells in the PVWM (A) and IGWM (B), Olig2 positive cells in the PVWM (C) and IGWM (D), Iba-1 positive cells (E) and GFAP positive cells in the PVWM (F), TNF-α positive cells in the PVWM, (G) and caspase-3 positive cells in the PVWM (H). *P <0.05, **P <0.01, ***P <0.001 versus Sal-Sham controls, # P <0.05 versus LPS-Sham, § P <0.05 versus Sal-Asp. Data are mean ± SEM. Asp, asphyxia; CNPase, 2′,-3′-Cyclic-nuceotide 3′-phosphodiesterase; GFAP, glial fibrillary acidic protein; Iba-1, ionized calcium-binding adapter molecule-1; IGWM, intragyral white matter; LPS, lipopolysaccharide; Olig2, Oligodendrocyte transcription factor-2; PVWM, periventricular white matter; TNF-α, tumor necrosis factor-α; Sal, saline.

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