Figure 5

Time sequence of changes in fetal plasma IL-6, IL-10 and cortisol concentrations. The horizontal bars at the top of the figure show the chronic infusions of LPS or saline. The arrows represent the times of the three LPS bolus doses (B1, B2 and B3). The vertical dashed line shows the time of the 15 minute period of umbilical cord occlusion in the asphyxia groups. Data were not available in the LPS-Sham group for the 11 am time point on day five. Data are mean ± SEM. *P <0.05. A) Sal-Sham versus LPS-Sham; B) Sal-Sham versus LPS-Asp; C) LPS-Sham versus Sal-Asp; D) LPS-Sham versus LPS-Asp; E) Sal-Asp versus LPS-Asp. Asp, asphyxia; IL, interleukin; LPS, lipopolysaccharide; Sal, saline.