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Table 2 Arterial pH, blood gases, lactate, and glucose values before during and after umbilical cord occlusion

From: Synergistic white matter protection with acute-on-chronic endotoxin and subsequent asphyxia in preterm fetal sheep

 

Group

Baseline

5 min

12 min

10 min post

2 h post

pH

S-A

7.35 ± 0.00

7.02 ± 0.01

6.92 ± 0.00

7.21 ± 0.00

7.36 ± 0.00

 

L-A

7.36 ± 0.00

6.98 ± 0.01§

6.90 ± 0.00

7.22 ± 0.00

7.36 ± 0.00

paCO 2 (mmHg)

S-A

48 ± 1.1

90.2 ± 2.9

111.4 ± 3.1

45.3 ± 0.3

46.5 ± 0.8

 

L-A

47.6 ± 1.2

95.7 ± 4.7

108.6 ± 6.5

46.4 ± 1.4

49.2 ± 0.9

paO 2 (mmHg)

S-A

24.6 ± 0.8

8.5 ± 0.9

8.1 ± 1.1

34.6 ± 1.3

25.1 ± 0.8

 

L-A

24.8 ± 0.8

7.1 ± 0.4

9.4 ± 0.6

33.1 ± 1.0

25 ± 0.9

Lactate (mmol/L)

S-A

0.87 ± 0.1

3.4 ± 0.2

4.6 ± 0.3

4.3 ± 0.5

1.2 ± 0.3

 

L-A

0.55 ± 0.1

3.3 ± 0.4

3.9 ± 0.7

4.7 ± 0.2

0.8 ± 0.1

Glucose (mmol/L)

S-A

1.1 ± 0.0

0.4 ± 0.1

0.9 ± 0.1

1.7 ± 0.2

1.2 ± 0.1

 

L-A

0.9 ± 0.1

0.4 ± 0.1

0.5 ± 0.1

1.6 ± 0.1

1.0 ± 0.1

  1. Post values are times after umbilical cord occlusion. S-A = Sal-Asp (saline infusion + saline boluses + 15 minutes of umbilical cord occlusion, n = 9); L-A = LPS-Sham (LPS infusion + LPS boluses + 15 minutes of umbilical cord occlusion, n = 8). LPS, lipopolysaccharide; paCO2, fetal arterial pressure of CO2 (mmHg); paO2, fetal arterial pressure of oxygen (mmHg). § P <0.05 versus Sal-Asp. Data are mean ± SEM.