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Figure 7 | Journal of Neuroinflammation

Figure 7

From: Deficiency of complement receptors CR2/CR1 in Cr2 -/-mice reduces the extent of secondary brain damage after closed head injury

Figure 7

Peripheral levels of selected biomarkers and inflammatory mediators in wild-type (WT) and Cr2 -/- mice at 24 hours after closed head injury or sham surgery. Serum and plasma samples were analyzed by mouse-specific ELISA. Final mediator concentrations were normalized by total protein content of the samples, as described in the Materials and methods section. Head-injured mice showed a significant increase in mediator levels at 24 hours, compared to sham-injured animals (*P <0.05). However, there was no difference in concentrations between head-injured WT and Cr2 -/- mice. Data are shown as mean values ± SD and are representative of n = 22 WT and n = 13 Cr2 -/- mice.

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