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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Impact of the neutrophil response to granulocyte colony-stimulating factor on the risk of hemorrhage when used in combination with tissue plasminogen activator during the acute phase of experimental stroke

Figure 4

MMP-9 release from peripheral neutrophil degranulation of purified rat neutrophils after 30 minutes ex vivo tPA stimulation at 24 and 72 hours of in vivo ischemia. Representative gelatin zymogram showing MMP-9 release in supernatant (a) and bar graphs representing mean values and SEM of 92 kDa proMMP-9 content (arbitrary unit by densitometry) (b). n = 4 per group, *P <0.05 versus PBS in control conditions; #P <0.05 versus G-CSF in ischemia/reperfusion conditions. CON: control group; GCSF: in vivo GCSF-administered group; IS, in vivo ischemia-reperfusion group; IS GCSF: in vivo ischemia-reperfusion group with GCSF administration; MM, molecular marker, PBS: non tPA stimulated control group, SEM standard error of the mean.

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