Figure 1
Fourteen day prophylactic acetate supplementation alters CD73 levels, CD73 activity, and A 2A receptor levels. Panel A shows representative images of the western blot analysis for CD73, adenosine kinase (AK), A2A receptor (A2AR), and α-tubulin. Panel B and C show CD73 levels and CD73 activity, while Panel D and E show AK levels and A2AR levels, respectively. All values represent the means ± SD, n = 6, 12, 6 for artificial cerebrospinal fluid (aCSF), lipopolysaccharide (LPS) and LPS + glyceryl triacetate (GTA) groups, respectively. Statistical significance set at P ≤0.05 and the symbol ‘a’ represents a difference compared to the aCSF group and ‘b’ represents a difference compared to the LPS group.