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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Acetate supplementation modulates brain adenosine metabolizing enzymes and adenosine A2Areceptor levels in rats subjected to neuroinflammation

Figure 3

Interventional acetate supplementation alters CD73 levels, CD73 activity, and A 2A receptor levels. Rats were infused with lipopolysaccharide (LPS) and were divided into two groups; beginning treatment with water or glyceryl triacetate (GTA) beginning on day 14. Panel A shows representative images of the western blot analysis for CD73, AK, A2A receptor (A2AR), and α-tubulin. Panel B and C show CD73 levels and CD73 activity, while Panel D and E show adenosine kinase (AK) and A2AR levels, respectively. Data represent mean ± SD, n = 8, 6 for LPS + H2O and LPS + GTA groups, respectively. The asterisk (*) represents statistical difference compared to LPS + H2O group (P ≤0.05).

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