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Table 1 Concentrations of sHLA-II in cerebrospinal fluid (CSF) and saliva in multiple sclerosis patient subgroups and controls (unit/ml)

From: Soluble HLA measurement in saliva and cerebrospinal fluid in Caucasian patients with multiple sclerosis: a preliminary study

  

CSF

Saliva

  

Study group

Number

Mean ± std dev

Mean ± std dev

t-value

p-value

RRMS-total

13

369 ± 16

386 ± 52

.70

.70

RRMS-C(+)

5

356 ± 26

380 ± 51

.44

.67

RRMS-C(-)

8

377 ± 18

390 ± 77

.56

.59

controls

52

----

222 ± 18

8.68

<.0005*

  1. RRMS = relapsing remitting multiple sclerosis
  2. (+) = contrast enhancement by MRI of brain (active plaque formation)
  3. (-) = without contrast enhancing plaques by MRI (inactive)
  4. *Comparison of saliva sHLA-II in patients (386 ± 52) vs. controls (222 ± 18)
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Journal of Neuroinflammation

ISSN: 1742-2094