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Table 1 Concentrations of sHLA-II in cerebrospinal fluid (CSF) and saliva in multiple sclerosis patient subgroups and controls (unit/ml)

From: Soluble HLA measurement in saliva and cerebrospinal fluid in Caucasian patients with multiple sclerosis: a preliminary study

   CSF Saliva   
Study group Number Mean ± std dev Mean ± std dev t-value p-value
RRMS-total 13 369 ± 16 386 ± 52 .70 .70
RRMS-C(+) 5 356 ± 26 380 ± 51 .44 .67
RRMS-C(-) 8 377 ± 18 390 ± 77 .56 .59
controls 52 ---- 222 ± 18 8.68 <.0005*
  1. RRMS = relapsing remitting multiple sclerosis
  2. (+) = contrast enhancement by MRI of brain (active plaque formation)
  3. (-) = without contrast enhancing plaques by MRI (inactive)
  4. *Comparison of saliva sHLA-II in patients (386 ± 52) vs. controls (222 ± 18)