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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human β-amyloid

Figure 3

Astrocyte activation following Aβ infusion. WT and IL1raKO mice were infused with Aβ or vehicle, and brains prepared as in Figure 2. A) Levels of the pro-inflammatory astrocyte-derived cytokine S100B showed a similar degree of upregulation in Aβ-infused IL1raKO and WT mice. B) Numbers of GFAP-positive astrocytes were increased to a similar degree in both WT and IL1raKO mice infused with Aβ. (error bars = SEM; p > 0.05 between Aβ-infused IL1raKO and WT mice).

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