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Table 1 Quantification of CX3CR1 mRNA expressing cells per square unit in rat EAE lesions (mean ± SEM)

From: CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin

 

NWM

PPWM

EA

LA

DM

Density of silver grains* per 1.9 × 10 4 μm 2

39.4 ± 8.2

70.8 ± 7.2

220.3 ± 17.4a

276.3 ± 14.8b

208.4 ± 18.3a

Total number of GSI-B4+ cells per 1.9 × 10 4 μm 2

11.0 ± 1.5

18.6 ± 1.6

65.3 ± 5.3a

68.1 ± 3.3a

59.8 ± 2.4a

Number of GSI-B4+/CX 3 CR1+ cells per 1.9 × 10 4 μm 2

5 ± 0.9

12.4 ± 1.3

46.1 ± 7.4a

50.7 ± 3.3a

46.0 ± 3.8a

Number of GSI-B4-/CX 3 CR1+ cells per 1.9 × 10 4 μm 2

0 ± 0

0 ± 0

0.8 ± 0.3

2.1 ± 0.7a

0.8 ± 0.4

  1. *Silver grains: defined as areas exceeding the mean background level + 11 SD
  2. a Statistically significant against NWM and PPWM
  3. bStatistically significant against NWM, PPWM, EA and DM