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Figure 7 | Journal of Neuroinflammation

Figure 7

From: 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia

Figure 7

Effect of AICAR in normalization of LPS-, or SMase- and/or Aβ peptide- (25–35) induced decreases in cellular glutathione and total mercaptans (thiol group containing compounds). Figure A shows a histogram plot of NO released after treatment with LPS or SMase and/or Aβ peptide, either in the presence or absence of AICAR (1 mM). Figure B shows corresponding levels of glutathione (in light colored bars) and total mercaptans (dark colored bars).

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