Table 1 Phagocytic and antigen presenting cell responses of immune cells. Note: ND, assay not performed; +/-, weak response; +, modest response; ++, strong response
From: The microglial "activation" continuum: from innate to adaptive responses
Surface marker | Phagocytosis | APC function | References |
|---|---|---|---|
CD36 | ++ | + | [91] [92] [93] |
CD40 | ND | ++ | [58] [94] [95] |
CD80 | ND | ++ | [94] [95] [96] |
CD86 | ND | ++ | [94] [95] [96] |
MHC II | ND | ++ | [94] |
CD11c | ND | ++ | [58] |
CD40L | +/- | ++ | [58] [80] |
Cytokine | Â | Â | Â |
IL-1β | ND | ++ | [97] |
IL-6 | ND | ++ | [98] |
IL-12 | ND | ++ | [98] [97] |
TNF-α | + | ++ | [98] [80] [97] |
IFN-γ | -/+ | ++ | [80] |
IL-4 | ++ | -/+ | [80] |
IL-10 | ++ | -/+ | [80] |
TGF-β1 | ++ | ND | [99] |