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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Astrocyte production of the chemokine macrophage inflammatory protein-2 is inhibited by the spice principle curcumin at the level of gene transcription

Figure 5

Curcumin but not EGCG inhibits MIP-2 mRNA expression. Confluent cultures of astrocyte were stimulated with LPS (5 μg/ml) in the presence or absence of varying doses of curcumin (10-5-10-7M), EGCG (10–3), or appropriate vehicle (0.05% ethanol for curcumin, DMSO for EGCG). mRNA was then extracted, reverse transcribed and amplified using mouse MIP-2 primers.

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