Cytokine production by brain slices from transgenic mouse models of AD at 15 months of age. Freshly harvested brain slices were incubated in neurobasal medium with B27 supplement. Media was collected after 24 hours, and cytokine levels measured. Mean concentrations (N = 15) +/- standard error are expressed in picograms per milligram of protein. P < 0.05 was considered statistically significant.