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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Aβ immunotherapy

Figure 4

Representative pictures of Thioflavin-S-stained Aβ plaques (lightly stained areas) decorated with ramified microglia immunostained with anti-mouse CD45 (black stain) in the neo cortex of untreated (A) 9-month-old APP/IL-1 R1-/- and (B) 15-month-old APP/IL-1 R1-/-; (C) 9-month-old APP/IL-1 R1+/- and (D) 15-month-old APP/IL-1 R1+/-; (E) 9-month-old wild type Tg2576 mice (IL-1 R1+/+) and (F) 15-month-old wild type Tg2576 mice (IL-1 R1+/+). (A, B, C, D, E, F magnification = 400×).

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Journal of Neuroinflammation

ISSN: 1742-2094