Figure 4

Dexamethasone reduces the levels of IL-6 in pathogenic Aβ-treated HCSM cells. Near confluent cultures of HCSM cells were incubated for six days in the presence or absence of 25 μM Dutch mutant Aβ40 with or without daily administration of anti-inflammatory drug (1 μM final concentration). The cell culture medium was collected and the level of IL-6 present in the medium was measured by ELISA analysis. The data presented are the mean ± S.D. of triplicate samples from two separate experiments.