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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Fibrillar beta-amyloid peptide Aβ1–40 activates microglial proliferation via stimulating TNF-α release and H2O2 derived from NADPH oxidase: a cell culture study

Figure 3

Microglial proliferation stimulated by PMA. Microglial cultures were incubated with 10 pg/ml of the NADPH oxidase activator phorbol 12-myristate 13-acetate (PMA), alone or together with the NADPH oxidase inhibitor apocynin (10 μM), or the hydrogen peroxide converter catalase (60 IU/ml) for 24 hours; then microglial cells were counted and their numbers were expressed as percentage of cell number at the start of the treatment, or time'0'. The dashed line indicates cell number at time '0'. Data are expressed as mean of 4 experiments ± standard error, Statistical analysis used: Student's t-test, p < 0.05; * – significant difference compared to the control; # – significant difference compared to samples treated with PMA only.

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