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Table 2 sPLA2-IIA-positive astrocytes in hippocampus and inferior temporal gyrus of Alzheimer (AD) and nondemented (ND) subjects.

From: Secretory PLA2-IIA: a new inflammatory factor for Alzheimer's disease

Brain region Dentate gyrus CA3 region Inferior temporal gyrus
Subjects AD ND AD ND AD ND
Total sPLA 2 -IIA-positive astrocytes 50.82 ± 9.001,*** 1.27 ± 0.96 24.11 ± 5.15*** 0.00 12.86 ± 2.90*** 1.99 ± 0.56
Plaque-associated sPLA 2 -IIA-positive astrocytes 2 0.66 ± 0.21* 0.00 1.59 ± 0.38** 0.00 8.60 ± 2.74* 0.51 ± 0.35
  1. 1Astrocyte counts are given as percent of all GFAP-positive astrocytes. Values are expressed as mean ± SD.
  2. 2Plaque-associated astrocytes were identified by co-staining with thioflavin S
  3. *, **, ***Value is significantly different from corresponding ND value (Student's t test): *p < 0.01; **p < 0.005; ***p < 0.001