Table 4 Associations of AD with HLA-B7 and HLA-Cw*0702 by APOE 4 status
From: Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity?
Allele | APOE 4 status | Proportions of alleles | Adjusted† odds ratios of AD (95% CI, p) | |
|---|---|---|---|---|
Controls | AD | |||
HLA-B7 | Positive | 14/110 | 42/246 | 1.7 (0.8–3.55, 0.19) |
Negative | 28/288 | 30/146 | 2.8 (1.5–5.2, 0.002) | |
All | 42/398 | 72/392 | 2.3 (1.4–3.7, 0.001) | |
HLA-Cw*0702 | Positive | 14/110 | 45/244 | 1.7 (0.8–3.6, 0.15) |
Negative | 34/288 | 31/146 | 2.2 (1.2–4.0, 0.01) | |
All | 48/398 | 76/390 | 2.0 (1.3–3.1, 0.003) | |