Table 5 Associations of AD with HLA-B7 and HLA-Cw*0702 by zygosity
From: Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity?
Allele | Homozygotes/heterozygotes/negatives(n) | Unadjusted† odds ratios of AD (95% CI, p) (versus negatives) | |
|---|---|---|---|
Controls | AD | ||
HLA-B7 | 0/42/157 | 7/58/131 | Heterozygotes: 1.7 (1.02–2.7, 0.04) |
Homozygotes: 18.0 (1.6–202, 0.0045) | |||
HLA-Cw*0702 | 1/46/152 | 9/58/128 | Heterozygotes: 1.5 (0.9–2.4, 0.09) |
Homozygotes: 10.7 (1.6–72.0, 0.007) | |||