Table 1 Treatment with IFN-γ reduces neuronal survival following incubation with amyloid-β1-42. SH-SY5Y cells or primary neuronal cell cultures were pre-treated with IFN-γ (1 ng/ml) for 24 hours prior to the addition of amyloid-β peptides as shown. Cell survival was determined using the WST-1 test after 24 hours (cell lines) or 4 days (primary neuronal cultures). Each value is the mean percentage cell survival ± SD from triplicate experiments repeated 3 times (9 observations). ** = Neuronal survival significantly less than untreated neurons incubated with amyloid-β1-42 (p < 0.05).