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Table 2 Expression of apoptotic genes in HSV-infected TLR2KO microglial cells.

From: Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia

Symbol

Gene

Fold change

  

8 h

16 h

Tnfsf10

TNF ligand superfamily member 10

8.66

5.59

Casp12

Caspase-12

4.15

1.00

RipK2

Receptor (Tnfrsf)-interacting kinase2

3.38

2.87

Casp8ap2

Caspase-8-associated protein 2

3.36

0.66

Fasl

Fas ligand

3.15

1.37

Casp3

Caspase-3

2.91

1.46

Tnf

Tumor necrosis factor

2.71

1.35

Cflar

Casp-8 and FADD-like apoptosis regulator

2.50

0.90

Tnfrsf5

TNF superfamily member 5

2.35

0.93

Bag4

BCL2-associated athanogene 4

2.16

0.58

Bad

Bcl-associated death promoter

-3.00

-5.07

Akt

Thymoma viral proto-oncogene1

-3.76

-2.56

Als2cr2

Als chromosome region candidate 2

-3.97

-2.38

Bax

Bcl2-associated X protein

-2.35

-1.49

Bcl10

B-cell leukemia/lymphoma 10

-2.71

-3.44

Birc5

Baculoviral IAP repeat-containing 5

-2.19

-8.87

Bcl2l14

Bcl2-like 14 (apoptosis facilitator)

-2.08

-4.08

Bid

BH3 interacting domain death agonist

-0.97

-2.21

Bnip3l

BCL2/adenovirus E1B-interacting protein

-4.94

-5.14

Birc6

Baculoviral IAP repeat-containing 6

-1.35

-3.19

Bnip2

BCL2/adenovirus E1B-interacting protein

-1.04

-2.56

Api5

Apoptosis inhibitor 5

-4.01

-2.56

Dsip1

TSC22 domain family 3

-2.55

-1.50

Cideb

Cell-death inducing DNA fragmentation factor 2

-1.78

-3.42

Cradd

CASP2 and RIPK1 adaptor domain containing protein

-1.54

-6.32

Fadd

Fas-associated death domain

-1.21

-2.92

Faim

Fas apoptotic inhibitory molecule

-1.81

-3.18

Hells

Helicase lymphoid specific

-0.84

-2.24

Il10

Interleukin 10

-1.27

-2.21

Mapk8ip1

MAP kinase interacting protein 1

-0.87

-5.75

Zc3hc1

C3HC type zinc finger protein

-0.93

-2.25

Nfkb1

NF-κB

-1.92

-1.55

Rnf7

Ring finger protein 7

-2.81

-2.31

Pak7

P21 (CDKN1A)-activated kinase 7

-0.85

-2.03

Traf3

TNF receptor-associated factor 3

-6.31

-2.71

Tnfrsf21

TNF receptor superfamily member 21

-1.87

-1.75

Trp53

P53

-2.80

-1.17