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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE

Figure 1

Sampling of rats from various clinical stages of MOG-EAE. Mean clinical score in female DA rats (n = 30), evaluated daily 8–29 days after immunization with 20 μg recombinant rat MOG in incomplete Freund's adjuvant. The arrows indicate selected time-points at which subsequent kinetic analyses were performed. Rats (n = 3/time-point) which conformed in the clinical score curve were chosen for histopathology and evaluation of CCR1, CCR2 and CCR5 mRNA expression in the spinal cord. Vertical bars represent mean and standard error of the mean.

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