C1q, C3, and C4 protein levels are elevated in Tg-SwDI mice thalamic region. Western blot analysis of complement proteins was performed using rabbit anti-C1q (A), rat anti-C3 (B), and rat anti-C4 (C) antibodies. Data shown are mean ± S.D. (n ≥ 6). The increase of all three proteins in both regions of the transgenic over wild-type reached statistical significance (*p < 0.01) except C3 was undetectable in cortex. Representative western blots are shown below the quantitation.