Figure 2

MT-MMP mRNA expression in microglia sorted from CNS. Microglia were sorted from whole CNS preparations based on flow cytometric detection of the surface markers CD45^dim CD11b⁺. Values on the Y-axis are relative to expression of 18S rRNA, and normalized to the expression level of the unmanipulated microglia. The values are arbitrary and cannot be compared between panels. n = at least 4 in each group; NS: not significant; Unm.: unmanipulated; *: p ≤ 0.05.