Figure 6
TNFα and MMP-15 expression by microglia stimulated in vitro. Microglia isolated from 12 WT and 8 IFNγR-/- mice were pooled separately and dispersed at 2 × 105 cells per well. Cultured microglia were stimulated with IFNγ in media at varying concentrations, or media only as control. Each bar graph represents results from three identically treated wells. Values on the Y-axis are relative to expression of 18S rRNA, and normalized to the expression level of the each control group, respectively. The values are arbitrary and cannot be compared between panels. U: units; NS: not significant; *: p ≤ 0.05.