Figure 3
From: Developmental stage of oligodendrocytes determines their response to activated microglia in vitro
LPS-activated microglia induce OPC cell death. OPCs were cultured in combination with microglia (A). Dead OPCs were not able to be quantified due to scattered debris (B), so OPC survival was measured by counting the number of live OPCs. LPS or microglia alone had no effect on OPC survival but microglia activated with LPS significantly reduced OPC survival (C, * = p < 0.05 from control, Tukey's, error bars = SEM).