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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Osteopetrotic (op/op) mice have reduced microglia, no Aβ deposition, and no changes in dopaminergic neurons

Figure 2

Quantification of CD11b expression in the hippocampus and substantia nigra. Computer assisted quantification of CD11b immunoreactivity demonstrated a significant difference in the hippocampus between WT (n = 3) and op/op (n = 3) mice at 30 days of age. This was also seen in the substantia nigra. Note the lower values in the substantia nigra compared to the hippocampus in both WT and op/op mice. All values are expressed as mean ± SEM and statistical significance was determined using the Mann Whitney U non-parametric test of significance. ROI – region of interest.

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Journal of Neuroinflammation

ISSN: 1742-2094