TY - JOUR AU - Strockbine, N. A. AU - Marques, L. R. M. AU - Newland, J. W. AU - Smith, H. W. AU - Holmes, R. K. AU - O'Brien, A. D. PY - 1986 DA - 1986// TI - Two toxin-converting phages from Escherichia coliO157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities JO - Infect Immun VL - 53 ID - Strockbine1986 ER - TY - JOUR AU - Richardson, S. E. AU - Karmali, M. A. AU - Becker, L. E. AU - Smith, C. R. PY - 1988 DA - 1988// TI - The histopathology of the hemolytic uremic syndrome associated with verocytotoxin-producing Escherichia coliinfections JO - Hum Pathol VL - 19 UR - https://doi.org/10.1016/S0046-8177(88)80093-5 DO - 10.1016/S0046-8177(88)80093-5 ID - Richardson1988 ER - TY - JOUR AU - Upadhyaya, K. AU - Barwick, K. AU - Fishaut, M. AU - Kashgarian, M. AU - Siegel, N. J. PY - 1980 DA - 1980// TI - The importance of nonrenal involvement in hemolytic-uremic syndrome JO - Pediatrics VL - 65 ID - Upadhyaya1980 ER - TY - JOUR AU - Richardson, S. E. AU - Rotman, T. A. AU - Jay, V. AU - Smith, C. R. AU - Becker, L. E. AU - Petric, M. AU - Olivieri, N. F. AU - Karmali, M. A. PY - 1992 DA - 1992// TI - Experimental verocytotoxemia in rabbits JO - Infect Immun VL - 60 ID - Richardson1992 ER - TY - JOUR AU - Zoja, C. AU - Corna, D. AU - Farina, C. AU - Sacchi, G. AU - Lingwood, C. AU - Doyle, M. P. AU - Padhye, V. V. AU - Abbate, M. AU - Remuzzi, G. PY - 1992 DA - 1992// TI - Verotoxin glycolipid receptors determine the localization of microangiopathic process in rabbits given verotoxin-1 JO - J Lab Clin Med VL - 120 ID - Zoja1992 ER - TY - JOUR AU - Barrett, T. J. AU - Potter, M. E. AU - Wachsmuth, I. K. PY - 1989 DA - 1989// TI - Continuous peritoneal infusion of Shiga-like toxin II (SLT II) as a model for SLT II-induced diseases JO - J Infect Dis VL - 159 UR - https://doi.org/10.1093/infdis/159.4.774 DO - 10.1093/infdis/159.4.774 ID - Barrett1989 ER - TY - JOUR AU - Fujii, J. AU - Kinoshita, Y. AU - Kita, T. AU - Higure, A. AU - Takeda, T. AU - Tanaka, N. AU - Yoshida, S. PY - 1996 DA - 1996// TI - Magnetic resonance imageing and histopathological study of brain lesions in rabbits given intravenous verotoxin 2 JO - Infect Immun VL - 64 ID - Fujii1996 ER - TY - JOUR AU - Ling, H. AU - Boodhoo, A. AU - Hazes, B. AU - Cummings, M. D. AU - Armstrong, G. D. AU - Brunton, J. L. AU - Read, R. J. PY - 1998 DA - 1998// TI - Structure of the Shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3 JO - Biochemistry VL - 37 UR - https://doi.org/10.1021/bi971806n DO - 10.1021/bi971806n ID - Ling1998 ER - TY - JOUR AU - Lingwood, C. A. PY - 1996 DA - 1996// TI - Role of verotoxin receptors in pathogenesis JO - Trends Microbiol VL - 4 UR - https://doi.org/10.1016/0966-842X(96)10017-2 DO - 10.1016/0966-842X(96)10017-2 ID - Lingwood1996 ER - TY - JOUR AU - O'Brien, A. D. AU - Tesh, V. L. AU - Donohue-Rolfe, A. AU - Jackson, M. P. AU - Olsnes, S. AU - Sandvig, K. AU - Lindberg, A. A. AU - Keusch, G. T. PY - 1992 DA - 1992// TI - Shiga toxin: biochemistry, genetics, mode of action and role in pathogenesis JO - Curr Top Microbiol Immunol VL - 180 ID - O'Brien1992 ER - TY - JOUR AU - Jones, N. L. AU - Islur, A. AU - Haq, R. AU - Mascarenhas, M. AU - Karmali, M. A. AU - Perdue, M. H. AU - Zanke, B. W. AU - Sherman, P. M. PY - 2000 DA - 2000// TI - Escherichia coliShiga toxins induce apoptosis in epithelial cells that is regulated by the bcl-2 family JO - Am J Physiol Gastrointest Liver Physiol VL - 278 ID - Jones2000 ER - TY - JOUR AU - Erwert, R. D. AU - Eiting, K. T. AU - Tupper, J. C. AU - Winn, R. K. AU - Harlan, J. M. AU - Bannerman, D. D. PY - 2003 DA - 2003// TI - Shiga toxin induces decreased expression of the anti-apoptotic protein Mcl-1 concomitant with the onset of endothelial apoptosis JO - Microb Pathog VL - 35 UR - https://doi.org/10.1016/S0882-4010(03)00100-1 DO - 10.1016/S0882-4010(03)00100-1 ID - Erwert2003 ER - TY - JOUR AU - Utsunomiya, I. AU - Ren, J. AU - Taguchi, K. AU - Ariga, T. AU - Tai, T. AU - Ihara, Y. AU - Miyatake, T. PY - 2001 DA - 2001// TI - Immunohistochemical detection of verotoxin receptors in nervous system JO - Brain Res Prot VL - 8 UR - https://doi.org/10.1016/S1385-299X(01)00091-5 DO - 10.1016/S1385-299X(01)00091-5 ID - Utsunomiya2001 ER - TY - JOUR AU - Streit, W. J. AU - Mrak, R. E. AU - Griffin, W. S. T. PY - 2004 DA - 2004// TI - Microglia and neuroinfalmmation: a pathological perspective JO - J Neuroinflammation VL - 1 UR - https://doi.org/10.1186/1742-2094-1-14 DO - 10.1186/1742-2094-1-14 ID - Streit2004 ER - TY - JOUR AU - Kreutzberg, G. W. PY - 1996 DA - 1996// TI - Microglia: a sensor for pathological events in the CNS JO - Trends Neurosci VL - 19 UR - https://doi.org/10.1016/0166-2236(96)10049-7 DO - 10.1016/0166-2236(96)10049-7 ID - Kreutzberg1996 ER - TY - JOUR AU - Allan, S. M. AU - Rothwell, N. J. PY - 2001 DA - 2001// TI - Cytokines and acute neurodegeneration JO - Nat Rev Neurosci VL - 2 UR - https://doi.org/10.1038/35094583 DO - 10.1038/35094583 ID - Allan2001 ER - TY - JOUR AU - Muñoz-Fernández, M. A. AU - Fresno, M. PY - 1998 DA - 1998// TI - The role of Tumor necrosis factor, interleukin 6, interferon-γ and inducible nitric oxide synthase in the development and pathology of the nervous system JO - Prog Neurobiol VL - 56 UR - https://doi.org/10.1016/S0301-0082(98)00045-8 DO - 10.1016/S0301-0082(98)00045-8 ID - Muñoz-Fernández1998 ER - TY - JOUR AU - Barone, F. C. AU - Arvin, B. AU - White, R. F. AU - Miller, A. AU - Webb, C. L. AU - Willette, R. N. AU - Lysko, P. G. AU - Feuerstein, G. Z. PY - 1997 DA - 1997// TI - Tumor necrosis factor-α A mediator of focal ischemic brain injury JO - Stroke VL - 28 UR - https://doi.org/10.1161/01.STR.28.6.1233 DO - 10.1161/01.STR.28.6.1233 ID - Barone1997 ER - TY - JOUR AU - Combs, C. K. AU - Kario, J. C. AU - Kao, S. -. C. AU - Landreth, G. E. PY - 2001 DA - 2001// TI - β-amyloid stimulation of microglia and monocytes results in TNFα-dependent expression of inducible nitric oxide synthase and neuronal apoptosis JO - J Neurosci VL - 21 ID - Combs2001 ER - TY - JOUR AU - Patel, N. S. AU - Paris, D. AU - Mathura, V. AU - Quadros, A. N. AU - Crawford, F. C. AU - Mullan, M. J. PY - 2005 DA - 2005// TI - Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease JO - J Neuroinflammation VL - 2 UR - https://doi.org/10.1186/1742-2094-2-9 DO - 10.1186/1742-2094-2-9 ID - Patel2005 ER - TY - JOUR AU - Hirsch, E. C. AU - Breidert, T. AU - Rousselet, E. AU - Hunot, S. AU - Hartmann, A. AU - Michel, P. P. PY - 2003 DA - 2003// TI - The role of glial reaction and inflammation in Parkinson's disease JO - Ann N Y Acad Sci VL - 991 UR - https://doi.org/10.1111/j.1749-6632.2003.tb07478.x DO - 10.1111/j.1749-6632.2003.tb07478.x ID - Hirsch2003 ER - TY - JOUR AU - Swarup, V. AU - Ghosh, J. AU - Duseja, R. AU - Ghosh, S. AU - Basu, A. PY - 2007 DA - 2007// TI - Japanese encephalitis virus infection decrease endogenous IL-10 production: correlation with microglial activation and neuronal death JO - Neurosci Lett VL - 420 UR - https://doi.org/10.1016/j.neulet.2007.04.071 DO - 10.1016/j.neulet.2007.04.071 ID - Swarup2007 ER - TY - JOUR AU - Wesselingh, S. L. AU - Takahashi, K. AU - Glass, J. D. AU - McArthur, J. C. AU - Griffin, J. W. AU - Griffin, D. E. PY - 1997 DA - 1997// TI - Cellular localization of tumor necrosis factor mRNA in neurological tissue from HIV-infected patients by combined reverse transcriptase/polymerase chain reaction in situ hybridization and immunohistochemistry JO - J Neuroimmunol VL - 74 UR - https://doi.org/10.1016/S0165-5728(96)00160-9 DO - 10.1016/S0165-5728(96)00160-9 ID - Wesselingh1997 ER - TY - JOUR AU - Yang, L. AU - Lindholm, K. AU - Konishi, Y. AU - Li, R. AU - Shen, Y. PY - 2002 DA - 2002// TI - Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways JO - J Neurosci VL - 22 ID - Yang2002 ER - TY - JOUR AU - Akassoglou, K. AU - Bauer, J. AU - Kassiotis, G. AU - Pasparakis, M. AU - Lassmann, H. AU - Kollias, G. AU - Probert, L. PY - 1998 DA - 1998// TI - Olihodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice. Models for multiple sclerosis with primary oligocendrogliopathy JO - Am J Pathol VL - 153 UR - https://doi.org/10.1016/S0002-9440(10)65622-2 DO - 10.1016/S0002-9440(10)65622-2 ID - Akassoglou1998 ER - TY - JOUR AU - Isogai, E. AU - Isogai, H. AU - Kimura, K. AU - Hayashi, S. AU - Kubota, T. AU - Fujii, N. AU - Takeshi, K. PY - 1998 DA - 1998// TI - Role of tumor necrosis factor alpha in gnotobiotic mice infected with an Escherichia coliO157:H7 strain JO - Infect Immun VL - 66 ID - Isogai1998 ER - TY - JOUR AU - Yutsudo, T. AU - Nakabayashi, N. AU - Hirayama, T. AU - Takeda, Y. PY - 1987 DA - 1987// TI - Purification and some properties of a Vero toxin from Escherichia coliO157:H7 that is immunologically unrelated to Shiga toxin JO - Microb Pathog VL - 3 UR - https://doi.org/10.1016/0882-4010(87)90034-9 DO - 10.1016/0882-4010(87)90034-9 ID - Yutsudo1987 ER - TY - JOUR AU - Oishi, H. AU - Takaoka, A. AU - Hatayama, Y. AU - Matsuo, T. AU - Sakata, Y. PY - 1985 DA - 1985// TI - Automated limulus amebocyte lysate (LAL) test for endotoxin analysis using a new Toxinometer ET-201 JO - J Parenter Sci Technol VL - 39 ID - Oishi1985 ER - TY - JOUR AU - Nitatori, T. AU - Sato, N. AU - Waguri, S. AU - Karasawa, Y. AU - Araki, H. AU - Shibanai, K. AU - Kominami, E. AU - Uchiyama, Y. PY - 1995 DA - 1995// TI - Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis JO - J Neurosci VL - 15 ID - Nitatori1995 ER - TY - JOUR AU - Takahashi, K. AU - Wesselingh, S. L. AU - Griffin, D. E. AU - McArthur, J. C. AU - Johnson, R. T. AU - Glass, J. D. PY - 1996 DA - 1996// TI - Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunohistochemistry JO - Ann Neurol VL - 39 UR - https://doi.org/10.1002/ana.410390606 DO - 10.1002/ana.410390606 ID - Takahashi1996 ER - TY - JOUR AU - Simpson, D. A. C. AU - Feeney, S. AU - Boyle, C. AU - Stitt, A. W. PY - 2000 DA - 2000// TI - Retinal VEGF mRNA measured by SYBR green I fluorescence: A versatile approach to quantitative PCR JO - Mol Vis VL - 6 ID - Simpson2000 ER - TY - JOUR AU - Reno, C. AU - Boykiw, R. AU - Martinez, M. L. AU - Hart, D. A. PY - 1998 DA - 1998// TI - Temporal alterations in mRNA levels for proteinases and inhibitors and their potential regulators in the healing medial collateral ligament JO - Biochem Biophys Res Commun VL - 252 UR - https://doi.org/10.1006/bbrc.1998.9734 DO - 10.1006/bbrc.1998.9734 ID - Reno1998 ER - TY - JOUR AU - Murata, T. AU - Yamawaki, H. AU - Hori, M. AU - Sato, K. AU - Ozaki, H. AU - Karaki, H. PY - 2001 DA - 2001// TI - Hypoxia impairs endothelium-dependent relaxation in organ cultured pulmonary artery JO - Eur J Pharmacol VL - 421 UR - https://doi.org/10.1016/S0014-2999(01)01015-9 DO - 10.1016/S0014-2999(01)01015-9 ID - Murata2001 ER - TY - JOUR AU - Wu, A. M. AU - Wu, J. H. AU - Singh, T. AU - Lai, L. -. J. AU - Yang, Z. AU - Herp, A. PY - 2006 DA - 2006// TI - Recognition factors of Ricinus communis agglutinin 1 (RCA1) JO - Mol Immunol VL - 43 UR - https://doi.org/10.1016/j.molimm.2005.09.008 DO - 10.1016/j.molimm.2005.09.008 ID - Wu2006 ER - TY - JOUR AU - Taylor, F. B. AU - Tesh, V. L. AU - DeBault, L. AU - Li, A. AU - Chang, A. C. K. AU - Kosanke, S. D. AU - Pysher, T. J. AU - Siegler, R. L. PY - 1999 DA - 1999// TI - Characterization of the baboon responses to Shiga-like toxin. Descriptive study of a new primate model of toxic responses to Stx-1 JO - Am J Pathol VL - 154 UR - https://doi.org/10.1016/S0002-9440(10)65380-1 DO - 10.1016/S0002-9440(10)65380-1 ID - Taylor1999 ER - TY - JOUR AU - Mizuguchi, M. AU - Tanaka, S. AU - Fujii, I. AU - Tanizawa, H. AU - Suzuki, Y. AU - Igarashi, T. AU - Yamanaka, T. AU - Takeda, T. AU - Miwa, M. PY - 1996 DA - 1996// TI - Neuronal and vascular pathology produced by verocytotoxin 2 in the rabbit central nervous system JO - Acta Neuropathol VL - 91 UR - https://doi.org/10.1007/s004010050423 DO - 10.1007/s004010050423 ID - Mizuguchi1996 ER - TY - JOUR AU - Goldstein, J. AU - Loidl, C. F. AU - Creydt, V. P. AU - Boccoli, J. AU - Ibarra, C. PY - 2007 DA - 2007// TI - Intracerebroventricular administration of Shiga toxin type 2 induces striatal neuronal death and glial alterations: An ultrastructural study JO - Brain Res VL - 1161 UR - https://doi.org/10.1016/j.brainres.2007.05.067 DO - 10.1016/j.brainres.2007.05.067 ID - Goldstein2007 ER - TY - JOUR AU - Aloisi, F. PY - 2001 DA - 2001// TI - Immune function of microglia JO - Glia VL - 36 UR - https://doi.org/10.1002/glia.1106 DO - 10.1002/glia.1106 ID - Aloisi2001 ER - TY - JOUR AU - Esolen, L. M. AU - Takahashi, K. AU - Johnson, R. T. AU - Vaisberg, A. AU - Moench, T. R. AU - Wesselingh, S. L. AU - Griffin, D. E. PY - 1995 DA - 1995// TI - Brain endothelial cell infection in children with acute fatal measles JO - J Clin Invest VL - 96 UR - https://doi.org/10.1172/JCI118306 DO - 10.1172/JCI118306 ID - Esolen1995 ER - TY - JOUR AU - Lee, D. Y. AU - Park, K. W. AU - Jin, B. K. PY - 2006 DA - 2006// TI - Thrombin induces neurodegeneration and microglial activation in the cortex in vivo and in vitro: Proteolytic and non-proteolytic actions JO - Biochem Biophys Res Commun VL - 346 UR - https://doi.org/10.1016/j.bbrc.2006.05.174 DO - 10.1016/j.bbrc.2006.05.174 ID - Lee2006 ER - TY - JOUR AU - Ekdahl, C. T. AU - Claasen, J. -. H. AU - Bonde, S. AU - Kokaia, Z. AU - Lindvall, O. PY - 2003 DA - 2003// TI - Inflammation is detrimental for neurogenesis in adult brain JO - Proc Natl Acad Sci USA VL - 100 UR - https://doi.org/10.1073/pnas.2234031100 DO - 10.1073/pnas.2234031100 ID - Ekdahl2003 ER - TY - JOUR AU - Chao, C. C. AU - Hu, S. AU - Ehrlich, L. AU - Peterson, P. K. PY - 1995 DA - 1995// TI - Interleukin-1 and tumor necrosis factor-α synergistically mediate neurotoxicity: Involvement of nitric oxide and of N-methyl-D-aspartate receptors JO - Brain Behav Immun VL - 9 UR - https://doi.org/10.1006/brbi.1995.1033 DO - 10.1006/brbi.1995.1033 ID - Chao1995 ER - TY - JOUR AU - Zhao, X. AU - Bausano, B. AU - Pike, B. R. AU - Newcomb-Fernandez, J. K. AU - Wang, K. K. W. AU - Shohami, E. AU - Ringger, N. C. AU - DeFord, S. M. AU - Anderson, D. K. AU - Hayes, R. L. PY - 2001 DA - 2001// TI - TNF-α stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures JO - J Neurosci Res VL - 64 UR - https://doi.org/10.1002/jnr.1059 DO - 10.1002/jnr.1059 ID - Zhao2001 ER - TY - JOUR AU - Venters, H. D. AU - Tang, Q. AU - Liu, Q. AU - VanHoy, R. W. AU - Dantzer, R. AU - Kelley, K. W. PY - 1999 DA - 1999// TI - A new mechanism of neurodegeneration: A proinflammatory cytokine inhibits receptor signaling by a survival peptide JO - Proc Natl Acad Sci USA VL - 96 UR - https://doi.org/10.1073/pnas.96.17.9879 DO - 10.1073/pnas.96.17.9879 ID - Venters1999 ER - TY - JOUR AU - Takeuchi, H. AU - Jin, S. AU - Wang, J. AU - Zhang, G. AU - Kawanokuchi, J. AU - Kuno, R. AU - Sonobe, Y. AU - Mizuno, T. AU - Suzumura, A. PY - 2006 DA - 2006// TI - Tumor necrosis factor-α induces neurotoxicity via glutamate release from hemichannels of activated microglia in an aoutocrine manner JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M600504200 DO - 10.1074/jbc.M600504200 ID - Takeuchi2006 ER - TY - JOUR AU - Ergonul, Z. AU - Hughes, A. K. AU - Kohan, D. E. PY - 2003 DA - 2003// TI - Induction of apoptosis of human brain microvascular endothelial cells by Shiga toxin 1 JO - J Infect Dis VL - 187 UR - https://doi.org/10.1086/345861 DO - 10.1086/345861 ID - Ergonul2003 ER - TY - JOUR AU - Pijpers, A. H. J. M. AU - Van Setten, P. A. AU - Van Den Heuvel, L. P. W. J. AU - Assmann, K. J. M. AU - Dijkman, H. B. P. M. AU - Pennings, A. H. M. AU - Monnens, L. A. H. AU - Van Hinsbergh, V. W. M. PY - 2001 DA - 2001// TI - Verocytotoxin-induced apoptosis of human microvascular endothelial cells JO - J Am Soc Nephrol VL - 12 ID - Pijpers2001 ER - TY - CHAP AU - Ramegowda, B. AU - Samuel, J. E. AU - Tesh, V. L. PY - 1999 DA - 1999// TI - Interaction of Shiga toxins with human brain microvascular endothelial cells: Cytokines as sensitizing agents BT - J Infect Dis ID - Ramegowda1999 ER - TY - JOUR AU - Eisenhauer, P. B. AU - Chaturvedi, P. AU - Fine, R. E. AU - Ritchie, A. J. AU - Pober, J. S. AU - Cleary, T. G. AU - Newburg, D. S. PY - 2001 DA - 2001// TI - Tumor necrosis factor alpha increases human cerebral endothelial cell Gb3and sensitivity to Shiga toxin JO - Infect Immun VL - 69 UR - https://doi.org/10.1128/IAI.69.3.1889-1894.2001 DO - 10.1128/IAI.69.3.1889-1894.2001 ID - Eisenhauer2001 ER - TY - JOUR AU - Stricklett, P. K. AU - Hughes, A. K. AU - Ergonul, Z. AU - Kohan, D. E. PY - 2002 DA - 2002// TI - Molecular basis for up-regulation by inflammatory cytokines of Shiga toxin 1 cytotoxicity and globotriaosylceramide expression JO - J Infect Dis VL - 186 UR - https://doi.org/10.1086/344053 DO - 10.1086/344053 ID - Stricklett2002 ER - TY - JOUR AU - Zhang, H. -. M. AU - Ou, Z. L. AU - Gondaira, F. AU - Ohmura, M. AU - Kojio, S. AU - Yamamoto, T. PY - 2001 DA - 2001// TI - Protective effect of anisodamine against Shiga toxin-1: Inhibition of cytokine production and increase in the survival of mice JO - J Lab Clin Med VL - 137 UR - https://doi.org/10.1067/mlc.2001.112507 DO - 10.1067/mlc.2001.112507 ID - Zhang2001 ER - TY - JOUR AU - Qian, L. AU - Xu, Z. AU - Zhang, W. AU - Wilson, B. AU - Hong, J. S. AU - Flood, P. M. PY - 2007 DA - 2007// TI - Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase JO - J Nueroinflammation VL - 4 UR - https://doi.org/10.1186/1742-2094-4-23 DO - 10.1186/1742-2094-4-23 ID - Qian2007 ER -