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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease

Figure 6

Double immunostaining of IgG extravasation and the expression of ZO-1. Cholesterol-enriched diet markedly decreased the immunopositive staining of ZO-1 (green) at the sites where IgG extravasation (red) was present. These effects were blocked by chronic ingestion of caffeine. Representative images taken from 2 rabbits in each group with 6 sections from each animal are shown. Bar = 20 μm.

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