Table 5 Numbers of "EAE-response CNS genes" regulated in particular disease phase compared to healthy rats. Differentially regulated genes were considered to be "EAE-response CNS genes", when they were not expressed in lymph nodes (based on own microarray experiments).
From: Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis
| acute – healthy | recovery – healthy | relapsing – healthy | |
|---|---|---|---|
| upregulated | |||
| 2-fold | 8 | 21 | 6 |
| 4-fold | 8 | 5 | 2 |
| 8-fold | 3 | 3 | 0 |
| downregulated | |||
| 2-fold | 42 | 59 | 34 |
| 4-fold | 20 | 15 | 2 |
| 8-fold | 7 | 4 | 1 |