Figure 1
From: GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice
Genotypes and GRK5 expression in TgAPPsw mice with reduced GRK5. Top panel, an example of the genotyping results for the WT (APPsw-/-/GRK5+/+), heterozygote GRK5KO (APPsw-/-/GRK5+/-), TgAPPsw (APPsw+/-/GRK5+/+), and the double mice (APPsw+/-/GRK5+/-) using the ascribed five primers. 500 base pair (bp) band, human APPsw; 425 bp band, WT GRK5; 200 bp band, inactivated GRK5. Bottom panels are representative Western blots for GRK5 and β-actin (internal control for the amounts of sample loaded), respectively, as indicated.