Figure 6
From: GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice
Colocalization of reactive astrocytes with Aβ plaques and IL-6 immunoreactivity in the TgAPPsw mice with reduced GRK5. Panels A-C, IF staining of Aβ+ plaques (A, red) and nearby GFAP+ reactive astrocytes (B, green), as well as their merged view (C) in the double mice. Scale bar: 50 μm for panels A-C. Panels D-F, IF staining of GFAP+ astrocytes (D, red) and colocalized IL-6-IR (E, green), as well as their merged view (F) in the double mice. Scale bar: 20 μm for panels D-F. Blue indicates reference DAPI staining of nuclei.