Figure 2
From: Acute hemorrhagic demyelination in a murine model of multiple sclerosis
Pathology of mouse brain coronal sections of 7 day TMEV infected C57BL/6J mice. A and B: 24 hours post intravenous irrelevant E7 peptide injection. C and D: 24 hours post intravenous VP2121–130 peptide injection. Red arrows demonstrate microhemorrhages, yellow arrows demonstrate sites of demyelination. E: CD8 T cell stain in the corpus callosum (cc) and hippocampus (hipp) 24 hours post intravenous VP2121–130 peptide injection. F: T1 Gadolinium enhanced MRI at the level of the hippocampus 24 hours post intravenous VP2121–130 peptide injection.