Figure 6
Immunostaining of neocortex for C1q and C3b components of complement, and concomitant staining of meninges for C1q and ThS. A. Representative images of cortex areas of coronal brain sections of mice immunized with mannan-Aβ28 or mannan-BSA, immunostained with antibodies specific for C1q and C3b components of complement. Original magnification, 20×, scale bar = 50 μm. B. Representative images of colocalization of vascular fibrillar Aβ detected with ThS (green) with C1q component of complement (red) in the meninges of coronal brain sections of mice immunized with mannan-Aβ28, mannan-BSA or non-immunized animals. Original magnification, 70×.