Figure 4

Comparison of dendritic cell CD11c immunolabelling with CD45 expression. A) Relatively few CD45+ cells are CD11c+ (arrowheads) in the SVZ. Bv = blood vessel. B, C) A much larger proportion of CD45+ cells are CD11c+ in the hippocampus and cerebellum. D) Cytoplasmic versus membrane labelling of CD11c and CD45, respectively. E) No CD11c+ cells in the lumbar spinal cord of a preclinical mouse, even in areas of CD45 activation. White outlines of the approximate border between grey and white matter were facilitated by the non-specific background staining in the gray matter (orange). F) CD11c+ dendritic cells were a subset of CD45+ cells in lumbar spinal cord white matter of chronic mice.