Figure 9
From: Hematopoietic cell activation in the subventricular zone after Theiler's virus infection
SVZ neuroblasts after TMEV infection. A) Dcx+ neuroblasts in control SVZ are bundled in tight clusters of chains, seen here in cross-section. B, C) Cell-cell contacts dissipate (asterisks) in the preclinical SVZ. Scale bar in C = 100 μm. D-G) examples of chains of Dcx+ cells (D, F, G) and individual Dcx+ cells emigrating from the SVZ in preclinical mice. Scale bars = 20 μm. H-I) PSA-NCAM immunohistochemistry in the dorsolateral SVZ reveals contiguous chains of cells in sham controls and loss of PSA-NCAM+ cells in preclinical mice after TMEV.