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Table 1 CD45+ cell activation.

From: Hematopoietic cell activation in the subventricular zone after Theiler's virus infection

 

Shams

Preclinical

Early Onset

Chronic

Olfactory Bulb

0.7 ± 0.1

1.6 ± 0.5

1.0 ± 0

1.5 ± 0.3

Anterior cortex

0.4 ± 0.1

2.2 ± 0.6

1.7 ± 0.3

1.3 ± 0.3

Meninges

0.9 ± 0.1

2.2 ± 0.6

1.7 ± 0.3

1.5 ± 0.3

SVZ

0.2 ± 0.1

2.3 ± 0.5

0.7 ± 0.3

0.5 ± 0.5

Striatum

0.9 ± 0.1

2.4 ± 0.4

1.3 ± 0.3

1.0 ± 0

Septum

0.2 ± 0.1

2.3 ± 0.5

0.7 ± 0.3

0.3 ± 0.3

Hippocampus

0.1 ± 0.1

1.8 ± 0.6

2.0 ± 1.0

2.6 ± 0.4

Choroid Plexus

0.8 ± 0.2

2.8 ± 0.2

2.0 ± 0.6

0.9 ± 0.1

3rd Ventricle

0.6 ± 0.2

2.6 ± 0.2

2.0 ± 1.0

2.0 ± 0.4

Fimbria/dorsal fornix

0.6 ± 0.2

2.2 ± 0.6

1.3 ± 0.9

2.0 ± 0.7

Amygdala

0

1.2 ± 0.7

0.3 ± 0.3

0

Thalamus

0

1.2 ± 0.7

0.3 ± 0.3

0.8 ± 0.3

Cerebellum

0

1.4 ± 0.4

1.3 ± 0.7

3.0 ± 0

Cervical Spinal Cord

0

2.0 ± 0.4

2.0 ± 1.0

3.0 ± 0

Thoracic Spinal Cord

0

2.2 ± 0.5

2.0 ± 1.0

2.5 ± 0.3

Lumbar Spinal Cord

0

2.4 ± 0.6

1.7 ± 0.3

2.5 ± 0.3

  1. CD45 activation semi-quantitative scoring summary from olfactory bulb through lumbar spinal cord using a 0–3 scoring system with a score of 3 being the greatest activation. See Fig. 1 for representative images.