Skip to main content


Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Figure 10 | Journal of Neuroinflammation

Figure 10

From: Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection

Figure 10

Schematic summary of cells, molecules, and processes affected by chronic T. gondii infection resulting in neuronal cell loss, inflammation, and behavioral and other neurologic abnormalities in mice. Parasites initially arrive at blood brain barrier in dendritic cells, travel into brain tissue and, within neurons, form bradyzoites in cysts. When the neuronal membrane is no longer intact, bradyzoites elicit an immune response as shown, which results in destruction of their growth and bystander cell death as shown.

Back to article page