Plaque complement activation and cognitive loss in Alzheimer's disease

Table 1 Subject summary statistics

Group	n	age (yrs)	education (yrs)	PMI (hrs)	Global neuropathology score
AN	17	79.91 ± 1.52	19.41 ± 0.94	7.48 ± 1.08	0.33 ± 0.09
MCI	12	86.71^a ± 1.93	18.83 ± 1.18	7.67 ± 2.54	0.39 ± 0.12
AD	17–18	89.35^a ± 1.77	17.78 ± 0.98	7.66 ± 1.27	1.02^b ± 0.13

AD and MCI subjects were older than AN subjects, but no significant differences were present between groups for educational level or PMI. The global neuropathology scores of the AD group differed from AN and MCI subjects. Data are expressed as means ± SEM. Abbreviations: AD, Alzheimer's disease; AN, aged normal subjects; MCI, subjects with mild cognitive impairment; PMI, post-mortem interval. (^ap < 0.05 vs. AN; ^bp < 0.05 vs. AN and MCI; *data were available from AD specimens for 18 C9-stained sections but only 17 iC3b-stained sections.)

ISSN: 1742-2094