Figure 7
Expression of PPAR-β mRNA in microglial cells after antibody-mediated demyelination. The antibody-mediated demyelination did not modify the cellular expression of PPAR-β analyzed by in situ hybridization. Macrophagic microglial cells labeled by ED1 were more numerous in cultures subjected to the demyelinating treatment (C compared to A and B, respectively). A, untreated control; B, complement treated (guinea pig serum, 25 μl/ml); C, treated with antibody (anti-MOG, 62.5 μg/ml) and complement. Bar = 50 μm.