TY - JOUR AU - Wei, Hans H. AU - Lu, Xi-Chun M. AU - Shear, Deborah A. AU - Waghray, Anu AU - Yao, Changping AU - Tortella, Frank C. AU - Dave, Jitendra R. PY - 2009 DA - 2009/08/05 TI - NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats JO - Journal of Neuroinflammation SP - 19 VL - 6 IS - 1 AB - Inflammatory cytokines play a crucial role in the pathophysiology of traumatic brain injury (TBI), exerting either deleterious effects on the progression of tissue damage or beneficial roles during recovery and repair. NNZ-2566, a synthetic analogue of the neuroprotective tripeptide Glypromate®, has been shown to be neuroprotective in animal models of brain injury. The goal of this study was to determine the effects of NNZ-2566 on inflammatory cytokine expression and neuroinflammation induced by penetrating ballistic-like brain injury (PBBI) in rats. SN - 1742-2094 UR - https://doi.org/10.1186/1742-2094-6-19 DO - 10.1186/1742-2094-6-19 ID - Wei2009 ER -