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Figure 1 | Journal of Neuroinflammation

Figure 1

From: NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats

Figure 1

NNZ-2566 treatment decreased inflammatory leukocyte filtration (H & E staining) after PBBI. Neutrophils (black arrows) and large macrophage-like cells (white arrows) were prominent in area surrounding the lesion cavity 3 days following PBBI (A, C). NNZ-2566 treatment (B, D) inhibited the infiltration of neutrophils and macrophage-like cells (B and D). By day 7, density of cellular infiltrate surrounding the lesion cavity was also reduced with the NNZ-2566 treatment (F) compared to the vehicle treatment (E).

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Journal of Neuroinflammation

ISSN: 1742-2094