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Table 1 Distribution and number of contrast enhancing lesions (CEL).

From: Beyond blood brain barrier breakdown – in vivodetection of occult neuroinflammatory foci by magnetic nanoparticles in high field MRI

Brain region Exclusively VSOP enhancement Gd-DTPA and VSOP enhancement Total number of CEL
Brain stem +++ +++++++++ 12
Periventricular ++ ++++++++++ 12
Midbrain   +++++++++ 9
Cerebellum ++ ++++++ 8
Olfactory bulb +++ +++++ 8
Cortex +++ +++ 6
  13 42 55
  1. Data are given from 14 mice after Gd-DTPA and VSOP administration, respectively. Three mice received VSOP only and are not included in the table. Each + refers to an individual animal.