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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Modulation of experimental autoimmune encephalomyelitis by endogenous Annexin A1

Figure 6

Impaired Th1 and Th17 cytokine production of MOG 35-55 -immunized AnxA1-/- mice. Levels of (A) IFN-γ, (B) IL-2, (C) TNF-α and (D) IL-17 in the cell supernatants of lymph node cells obtained from AnxA1+/+ and AnxA1-/- mice immunized with MOG35-55 and CFA and sacrificed after 14 days. Cells were stimulated with the indicated concentration of MOG35-55 for 4 days and the supernatants used for cytokine ELISA. Results are means ± SEM (n = 4/group). * p < 0.05, ** p < 0.01, representative of 3 experiments.

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