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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Expression of complement system components during aging and amyloid deposition in APP transgenic mice

Figure 1

Brain C1q, C3, factor B, C4 expression during aging in APP23 and control mice. Pair-wise comparison of transgenic and non-transgenic groups at each age using the 2-tailed t-test (* p = 0.05-0.01; ** p = 0.01-0.001; *** p = < 0.001); A: C1q expression (comparison of 3 months group with aged groups using Dunnetts test showed significance (p < 0.05) from 15 months (APP23) and 18 months (controls) onwards); B: C3 expression (comparison of 3 months group with aged groups showed significance from 24 months onwards (APP23 and controls)); C: factor B expression (comparison of 3 months group with aged groups showed significance from 18 months (APP23) and 24 months (controls) onwards); D: C4 expression (comparison of 3 months group with aged groups showed significance from 24 months onwards (APP23 and controls)).

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