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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Expression of complement system components during aging and amyloid deposition in APP transgenic mice

Figure 4

Complement immunostaining of AD and APP23 mouse brain. A: Neocortex (F2) of an AD brain: C1q, C3, C3d, C7 and C9 immunostaining of diffuse (red arrow), compact (violet arrow) and cored (blue arrow) amyloid plaques and neurofibrillary tangles (yellow arrow); bar = 50 μm; B: Neocortex of a 20 months old female APP23 mouse: C1q, C3 and C3d immunostaining of diffuse (red arrow) and compact (violet arrow) amyloid plaques; C7 immunostaining of the amyloid plaque periphery (yellow arrow); C9 staining: weak fluorescence above background (control), no specific staining of non-transgenic mice (control); bar = 100 μm.

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